ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation
Z. Li, Y. Wu, A. Bahreini, N. M. Priedigkeit, K. Ding, C. A. Sartorius, L. Miller, M. Rosenzweig, N. Wagle, J. K. Richer, W. J. Muller, L. Buluwela, S. Ali, Y. Fang, L. Zhu, , S. Oesterreich
This study shows ESR1 mutant breast cancers exhibit basal cytokeratin expression and immune activation, linked to chromatin reprogramming and paracrine signaling.
bioRxiv · Dec 29, 2020 · PreprintCancer Biology