Author

G. Carrington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Peckham· 2 shared A. D'Amico· 1 shared A. Hau· 1 shared A. Oldfors· 1 shared D. Casas-Mao· 1 shared E. Malfatti· 1 shared E. Zanoteli· 1 shared F. Muntoni· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

M. Peckham

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2 papers

Recent·Most cited

A Multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A.

G. Carrington, U. Fatima, I. Caramujo, T. Lewis, D. Casas-Mao, M. Peckham

This study uses multiscale techniques to reveal the molecular structure of autoinhibited KIF5A, showing how its C-terminal tail contributes to autoinhibition and how mutations affect this state.

bioRxiv · Jan 18, 2024Cell Biology

Human light meromyosin mutations linked to skeletal myopathies disrupt the coiled coil structure and myosin head sequestration

G. Carrington, A. Hau, S. Kosta, H. Dugdale, F. Muntoni, A. D'Amico, P. Van den Bergh, N. Romero, E. Malfatti, J. J. Vilchez, A. Oldfors, S. Pajusalu, K. Ounap, M. Giralt-Pujol, E. Zanoteli, , J. Ochala

This study investigates how mutations in MYH7 and MYH2 genes affect myosin structure and function, finding that they disrupt coiled-coil structure and increase ATP consumption without affecting contractile function.

bioRxiv · May 15, 2023 · PreprintPhysiology