N. Romero

Oxygen carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia-induced suppression and improve cancer immunotherapy

This study shows oxygen-carrying nanoemulsions and respiratory hyperoxia reduce tumor hypoxia, enhance T cell and NK cell infiltration, and improve cancer immunotherapy outcomes.

Human light meromyosin mutations linked to skeletal myopathies disrupt the coiled coil structure and myosin head sequestration

This study investigates how mutations in MYH7 and MYH2 genes affect myosin structure and function, finding that they disrupt coiled-coil structure and increase ATP consumption without affecting contractile function.

Calculation of ATP production rates using the Seahorse XF Analyzer

The paper develops a method to calculate ATP production rates from oxidative phosphorylation and glycolysis using Seahorse XF Analyzer data, enabling direct comparison of ATP sources in live cells.

Type I Interferon acts as a major barrier to the establishment of infectious bursal disease virus (IBDV) persistent infections

This paper shows that type I interferon inactivation enables IBDV to establish persistent infections in avian and human cells by reducing apoptosis.

Lamin-related congenital muscular dystrophy alters mechanical signaling and skeletal muscle growth

This study investigates how LMNA mutations affect skeletal muscle growth and mechanical signaling in muscle stem cells and mouse models, finding impaired differentiation and hypertrophy in LMNA-CMD.

SH3KBP1 scaffolds endoplasmic reticulum and controls skeletal myofibers architecture and integrity

This paper identifies SH3KBP1 as a regulator of myonuclear positioning and muscle fiber integrity through ER and T-tubule scaffolding, with implications for a CNM mouse model.