G. D. Chure

Coordination Between Cytoplasmic and Envelope Densities Shapes Cellular Geometry in Escherichia coli

This study develops and validates a biophysical model showing that constant ratios of cytoplasmic and membrane protein densities regulate Escherichia coli cell geometry through proteome partitioning and ribosome content.

First-principles prediction of the information processing capacity of a simple genetic circuit

The paper predicts the information processing capacity of a genetic circuit using a minimal model based on published data and compares it with experimental results in E. coli.

Connecting the dots between mechanosensitive channel abundance, osmotic shock, and survival at single-cell resolution

The paper quantifies the number of MscL channels required for E. coli survival after osmotic shock using single-cell fluorescence microscopy and finds that 500-700 channels per cell are needed for 80% survival.