G. D. Learn

A PMMA bone cement composite that functions as a drug-refillable depot for localized, multi-window chemotherapeutic treatment of bone cancer

This paper develops a refillable PMMA bone cement composite for localized, multi-window chemotherapy of bone cancer, showing sustained drug release and improved cytotoxicity compared to conventional methods.

Cyclodextrin polymer coatings resist protein fouling, mammalian cell adhesion, and bacterial attachment

Using nonthermal plasma treatment to improve quality and durability of hydrophilic coatings on hydrophobic polymer surfaces

This study uses nonthermal plasma treatment to enhance coating quality and durability on hydrophobic polymer surfaces by improving wettability and interfacial bonding.

Nonthermal plasma treatment of polymers modulates biological fouling but can cause material embrittlement

This study examines how nonthermal plasma treatment affects both surface and bulk properties of polymeric implants, finding benefits for biological fouling resistance but risks of material embrittlement with prolonged exposure.

Combination antibiotic delivery in PMMA provides sustained broad-spectrum antimicrobial activity and allows for post-implantation refilling

This paper develops a combination-antibiotic PMMA composite system that extends antimicrobial activity duration and allows post-implantation refilling, though it slightly reduces mechanical properties.