Ancestral acetylcholine receptor β-subunit forms homopentamers that prime before opening spontaneously
C. J. G. Tessier, R. M. Sturgeon, J. R. Emlaw, G. D. McCluskey, F. J. Perez-Areales, C. J. B. daCosta
This study shows that an ancestral acetylcholine receptor β-subunit can form homopentamers that open spontaneously, independent of the modern heteropentameric structure.
bioRxiv · Jan 12, 2022Biophysics