Author

G. E. Farrugia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. R. Pinto· 4 shared C. D. Cohen· 3 shared T. L. Gaynor· 3 shared C. Krstevski· 2 shared D. A. Skelly· 2 shared I. Hsu· 2 shared M. S. I. Dona· 2 shared A. El-Osta· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersCell Biology

A. R. Pinto

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4 papers

Recent·Most cited

Single-nucleus RNA sequencing reveals cellular and molecular dynamics of white and brown adipose tissue in a mouse model of type-2 diabetes

T. L. Gaynor, I. Hsu, C. Krstevski, G. E. Farrugia, M. S. Dona, C. D. Cohen, B. G. Drew, A. R. Pinto

This study uses single-nucleus RNA sequencing to analyze adipose tissue changes in a mouse model of type-2 diabetes, revealing altered cellular phenotypes and transcriptional circuits.

bioRxiv · Feb 6, 2024 · PreprintCell Biology

Maternal diet and gut microbiota influence predisposition to cardiovascular disease in the offspring

H. A. Jama, M. I. Dona, E. Dinakis, M. Nakai, M. R. Paterson, W. Shihata, C. Krstevski, C. D. Cohen, K. Weeks, G. E. Farrugia, C. Johnson, E. Salimova, D. Donner, H. Kiriazis, H. Kaipananickal, , F. Z. Marques

The paper shows that maternal fibre intake during pregnancy influences offspring cardiovascular health by shaping the gut microbiome and inducing epigenetic changes in the offspring's heart.

bioRxiv · Mar 12, 2022Microbiology

CLARA: A web portal for interactive exploration of the cardiovascular cellular landscape in health and disease

M. S. I. Dona, I. Hsu, T. S. Rathnayake, G. E. Farrugia, T. L. Gaynor, M. Kharbanda, D. A. Skelly, A. R. Pinto

CLARA provides a web portal for exploring cardiovascular cellular landscapes using single-cell transcriptomic data from mouse and human, enabling analysis of gene expression and cell interactions without specialized expertise.

bioRxiv · Jul 18, 2021 · PreprintCell Biology

High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy

M. A. McLellan, D. A. Skelly, M. S. I. Dona, G. T. Squiers, G. E. Farrugia, T. L. Gaynor, C. D. Cohen, R. Pandey, H. Diep, A. Vinh, N. A. Rosenthal, A. R. Pinto

This study uses single-cell transcriptomics to identify cellular drivers of cardiac fibrosis and hypertrophy under chronic stress, revealing sex-specific fibrogenic cell responses.

bioRxiv · Nov 25, 2019Cell Biology