Author

A. R. Pinto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Evolutionary Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 7 Research Focus:cell type annotation· 6 Assay:scRNA-seq· 4 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

G. E. Farrugia· 4 shared M. S. I. Dona· 4 shared C. D. Cohen· 3 shared D. A. Skelly· 3 shared I. Hsu· 3 shared T. L. Gaynor· 3 shared A. Vinh· 2 shared C. Krstevski· 2 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersCell Biology

G. E. Farrugia

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Single-nucleus RNA sequencing reveals cellular and molecular dynamics of white and brown adipose tissue in a mouse model of type-2 diabetes

T. L. Gaynor, I. Hsu, C. Krstevski, G. E. Farrugia, M. S. Dona, C. D. Cohen, B. G. Drew, A. R. Pinto

This study uses single-nucleus RNA sequencing to analyze adipose tissue changes in a mouse model of type-2 diabetes, revealing altered cellular phenotypes and transcriptional circuits.

bioRxiv · Feb 6, 2024 · PreprintCell Biology

Drivers of dispersal and diversification in bromeliads

I. M. Kessous, H. Farooq, W. Testo, M. F. Torres Jimenez, B. Neves, A. R. Pinto, F. Salgueiro, A. F. Costa, C. Bacon

This study examines how fruit morphology and habitat traits affect dispersal capacity and diversification rates in bromeliads, finding that berry fruits and environmental factors influence diversification.

bioRxiv · Nov 4, 2022 · PreprintEvolutionary Biology

Multi-omic analysis of the cardiac cellulome defines a vascular contribution to cardiac diastolic dysfunction in obese female mice

M. S. I. Dona, I. Hsu, A. I. Meuth, S. M. Brown, C. A. Bailey, C. G. Aragonez, B. Chandrasekar, L. A. Martinez-Lemus, V. G. DeMarco, L. A. Grisanti, I. Z. Jaffe, A. R. Pinto, S. B. Bender

This study shows that deleting the mineralocorticoid receptor in smooth muscle cells prevents obesity-induced coronary and cardiac diastolic dysfunction in female mice.

bioRxiv · Mar 24, 2022Physiology

Maternal diet and gut microbiota influence predisposition to cardiovascular disease in the offspring

H. A. Jama, M. I. Dona, E. Dinakis, M. Nakai, M. R. Paterson, W. Shihata, C. Krstevski, C. D. Cohen, K. Weeks, G. E. Farrugia, C. Johnson, E. Salimova, D. Donner, H. Kiriazis, H. Kaipananickal, , F. Z. Marques

The paper shows that maternal fibre intake during pregnancy influences offspring cardiovascular health by shaping the gut microbiome and inducing epigenetic changes in the offspring's heart.

bioRxiv · Mar 12, 2022Microbiology

Discovery of embryonically derived bipotent endothelial-macrophage progenitor cells in postnatal aorta

A. E. Williamson, S. Liyanage, M. Hassanshahi, M. S. I. Dona, D. Toledo-Flores, D. X. A. Tran, C. Dimasi, N. Schwarz, S. Fernando, T. Salagaras, A. Long, J. Kazenwadel, N. L. Harvey, G. R. Drummond, A. Vinh, , P. J. Psaltis

The paper identifies bipotent endothelial-macrophage progenitor cells in mouse aorta that contribute to postnatal vasculogenesis and macrophage formation.

bioRxiv · Oct 18, 2021 · PreprintCell Biology

CLARA: A web portal for interactive exploration of the cardiovascular cellular landscape in health and disease

M. S. I. Dona, I. Hsu, T. S. Rathnayake, G. E. Farrugia, T. L. Gaynor, M. Kharbanda, D. A. Skelly, A. R. Pinto

CLARA provides a web portal for exploring cardiovascular cellular landscapes using single-cell transcriptomic data from mouse and human, enabling analysis of gene expression and cell interactions without specialized expertise.

bioRxiv · Jul 18, 2021 · PreprintCell Biology

High-resolution transcriptomic profiling of the heart during chronic stress reveals cellular drivers of cardiac fibrosis and hypertrophy

M. A. McLellan, D. A. Skelly, M. S. I. Dona, G. T. Squiers, G. E. Farrugia, T. L. Gaynor, C. D. Cohen, R. Pandey, H. Diep, A. Vinh, N. A. Rosenthal, A. R. Pinto

This study uses single-cell transcriptomics to identify cellular drivers of cardiac fibrosis and hypertrophy under chronic stress, revealing sex-specific fibrogenic cell responses.

bioRxiv · Nov 25, 2019Cell Biology

Single cell transcriptional profiling reveals cellular diversity, communication, and sexual dimorphism in the mouse heart

D. A. Skelly, G. T. Squiers, M. A. McLellan, M. T. Bolisetty, P. Robson, N. Rosenthal, A. R. Pinto

This study uses scRNA-seq to analyze the mouse heart's non-myocyte cells, revealing cellular diversity, communication networks, and sexual dimorphism in gene expression.

bioRxiv · Oct 12, 2017Cell Biology