BiochemistrybioRxivPreprint
Production of a Highly Immunogenic Antigen from SARS-CoV-2 by Covalent Coupling of the Receptor Binding Domain of Spike Protein to a Multimeric Carrier
Argentinian AntiCovid Consortium, P. M. Berguer, M. Blaustein…·A. M. Zelada
This paper shows that coupling multiple SARS-CoV-2 RBD units to a multimeric carrier protein enhances immune response, leading to higher neutralizing antibody titers.
DOI 10.1101/2021.04.25.441271