Nanometer-Resolution Long-term Tracking of Single Cargos Reveals Dynein Motor Mechanisms
C. S. Peng, Y. Zhang, Q. Liu, G. E. Marti, Y.-W. A. Huang, T. C. Sudhof, B. Cui, S. Chu
This study uses single-particle tracking to analyze dynein motor behavior in live neurons, revealing that dynein switches between 1-5 motors and requires 2 ATP hydrolysis per step.
bioRxiv · Jan 5, 2022 · PreprintBiophysics