TCF7L2 Silencing Reprograms the 4D Nucleome of Colorectal Cancer Cells
M. A. Brown, G. A. Dotson, S. Ronquist, G. Emons, I. Rajapakse, T. Ried
This study shows that TCF4 silencing alters chromatin structure and gene expression in colorectal cancer cells, identifying EMT and E2F pathways as deregulated and c-JUN as a key transcription factor.
bioRxiv · May 12, 2020 · PreprintCancer Biology