Author

G. F. Ecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Cesar-Razquin· 1 shared A. Ingles-Prieto· 1 shared A. Ringler· 1 shared A. Stary-Weinzinger· 1 shared C.-H. Lardeau· 1 shared E. Girardi· 1 shared E. Hellsberg· 1 shared F. Kartnig· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Cesar-Razquin

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Author profile →

2 papers

Recent·Most cited

A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs

E. Girardi, A. Cesar-Razquin, K. Papakostas, S. Lindinger, J. Konecka, J. Hemmerich, S. Kickinger, F. Kartnig, A. Ingles-Prieto, G. Fiume, A. Ringler, C.-H. Lardeau, R. K. Kandasamy, S. Kubicek, G. F. Ecker, G. Superti-Furga

This study identifies SLC transporters critical for drug resistance using CRISPR screens in human cells, revealing widespread roles of SLCs in drug uptake and activity.

bioRxiv · Aug 8, 2019Cell Biology

A structural model of the human serotonin transporter in an outward-occluded state

E. Hellsberg, G. F. Ecker, A. Stary-Weinzinger, L. R. Forrest

This paper presents a homology model of the human serotonin transporter in an outward-occluded state, validated through molecular dynamics simulations, revealing distinct interactions compared to an outward-open conformation.

bioRxiv · May 13, 2019Biophysics