T cell degranulation and payload delivery are modulated in space and time
Kevin L. Scrudders, G. Graff, Laurent Limozin, Kheya Sengupta, Shalini T. Low-Nam
This study shows degranulation in T cells is regulated by physical and chemical factors, with insoluble particles transported directionally and CAR T cells having impaired particle centralization.
bioRxiv · Jul 26, 2026 · PreprintImmunology