The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
D. Minns, K. J. Smith, V. Alessandrini, G. Hardisty, L. Melrose, L. H. Jackson-Jones, A. S. MacDonald, D. J. Davidson, E. Gwyer Findlay
This study shows cathelicidin promotes Th17 differentiation by enhancing AHR and RORγt expression, increasing IL-17F production, and protecting Th17 cells from apoptosis.
bioRxiv · Apr 10, 2020Immunology