L. H. Jackson-Jones

Pericardial & Mediastinal Fat-Associated Lymphoid Clusters are rapidly activated in an alkane induced model of Systemic Lupus Erythematosus

This study identifies rapid B-cell activation in pericardial and mediastinal fat-associated lymphoid clusters in a pristane-induced SLE mouse model.

Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses

This study compares the efficacy of Vi polysaccharide and conjugated Vi vaccines in protecting against Salmonella Typhi, finding that conjugated vaccines sustain immune responses better over time.

Immunogenicity and Protective Efficacy of an Intranasal Live-attenuated Vaccine Against SARS-CoV-2 in Preclinical Animal Models

This study evaluates an intranasal live-attenuated vaccine against SARS-CoV-2 in mice and hamsters, showing high immunogenicity and complete protection from disease and viral shedding.

The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

This study shows cathelicidin promotes Th17 differentiation by enhancing AHR and RORγt expression, increasing IL-17F production, and protecting Th17 cells from apoptosis.

Neutrophils mediate the capture of peritoneal contaminants by fat-associated lymphoid clusters of the omentum

This study identifies FALC cover cells expressing CXCL1 that recruit neutrophils to neutralize peritoneal contaminants, confirmed in human appendicitis.

The pericardium promotes cardiac repair and remodelling post-myocardial infarction

This study shows that the pericardium promotes cardiac repair and reduces mortality after myocardial infarction by regulating inflammation and macrophage polarization.