The structure of a native orthobunyavirus ribonucleoprotein reveals a key role for viral RNA in maintaining its helical architecture
F. Hopkins, B. Alvarez-Rodriguez, G. Heath, K. Panayi, S. Hover, T. A. Edwards, J. Barr, J. Fontana
This paper determines the 3D structure of a native bunyavirus ribonucleoprotein (RNP) using cryo-EM, revealing a helical architecture stabilized by RNA rather than longitudinal contacts between nucleoprotein monomers.
bioRxiv · Oct 27, 2021 · PreprintMicrobiology