Author

G. Hedger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Assay:multiome· 1

Frequent Co-Authors

M. Sansom· 2 shared A. Baronina· 1 shared A. Pike· 1 shared C. Nasrallah· 1 shared C. Siebold· 1 shared E. P. Carpenter· 1 shared H. Koldsoe· 1 shared J. Shi· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

M. Sansom

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2 papers

Recent·Most cited

Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2 (PC2)

Q. Wang, G. Hedger, P. Aryal, M. Grieben, C. Nasrallah, A. Baronina, A. Pike, J. Shi, E. P. Carpenter, M. Sansom

This study investigates lipid interactions of PC2 using simulations and cryo-EM, identifying PIP and cholesterol binding sites.

bioRxiv · Mar 26, 2019Biophysics

Cholesterol interaction sites on the transmembrane domain of the hedgehog signal transducer and Class F G protein-coupled receptor Smoothened

G. Hedger, H. Koldsoe, M. Chavent, C. Siebold, R. Rohatgi, M. Sansom

The paper identifies cholesterol interaction sites on the transmembrane domain of the GPCR Smoothened using molecular dynamics simulations and free energy calculations.

bioRxiv · Aug 2, 2018Biophysics