Polypeptide collapse modulation and folding stimulation by GroEL-ES
M. M. Naqvi, M. J. Avellaneda, A. Roth, E. J. Koers, V. Sunderlikova, G. J. Kramer, H. S. Rye, S. J. Tans
This study shows GroEL-ES enhances polypeptide collapse, directly stimulating folding by pulling chains into its cavity and promoting compaction and folding transitions.
bioRxiv · Jun 17, 2020 · PreprintBiophysics