Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomes
M. Mitter, C. Gasser, Z. Takacs, C. H. C. Langer, W. Tang, G. Jessberger, C. T. Beales, E. Neuner, S. L. Ameres, J.-M. Peters, A. Goloborodko, R. Micura, D. W. Gerlich
This study introduces scsHi-C to analyze sister-chromatid interactions in human chromosomes, revealing frequent contacts at TAD boundaries and dynamic cohesin roles.
bioRxiv · Mar 10, 2020Cell Biology