Cancer BiologybioRxiv
Investigating the mechanisms underlying Bortezomib resistance
K. Zafeiropoulou, G. Kalampounias, S. Alexis…·P. Katsoris
This study investigates Bortezomib resistance mechanisms in prostate cancer cells, identifying restored proteasome activity, pro-survival pathways, autophagy induction, and reduced reactive oxygen species generation as key factors.
DOI 10.1371/journal.pone.0289904