Optimized tight binding between the S1 segment and KCNE3 is required for the constitutively open nature of the KCNQ1-KCNE3 channel complex
The paper identifies optimized interactions between the KCNQ1 S1 segment and KCNE3 that enable constitutive channel activity by regulating voltage sensor movement.
bioRxiv · Apr 5, 2021Biophysics