Author

G. L. Curran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

K. K. Kandimalla· 2 shared L. Wang· 2 shared P. H. Min· 2 shared V. J. Lowe· 2 shared L. Li· 1 shared M. Ebbini· 1 shared R. A. Siegel· 1 shared Z. WangiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

K. K. Kandimalla

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2 papers

Recent·Most cited

Amyloid Beta Peptides Inhibit Glucose Transport at the Blood-brain Barrier by Disrupting Insulin-Akt Pathway in Alzheimer's Disease

L. Wang, G. L. Curran, P. H. Min, L. Li, V. J. Lowe, K. K. Kandimalla

This study shows that amyloid-beta peptides inhibit glucose transport at the blood-brain barrier by disrupting the insulin-Akt pathway and increasing TXNIP expression.

bioRxiv · Nov 21, 2022 · PreprintPharmacology & Toxicology

Deconvolution of plasma pharmacokinetics from dynamic heart imaging data obtained by SPECT/CT imaging

Z. Wang, L. Wang, M. Ebbini, G. L. Curran, P. H. Min, R. A. Siegel, V. J. Lowe, K. K. Kandimalla

This paper develops a compartmental model to deconvolve plasma pharmacokinetics from dynamic heart imaging data, enabling accurate analysis of radiotracer kinetics without invasive plasma sampling.

bioRxiv · Nov 17, 2022 · PreprintPharmacology & Toxicology