The NUCKS1-SKP2-p21/p27 axis controls S phase entry
S. Hume, C. P. Grou, P. Lascaux, V. D'Angiolella, A. J. Legrand, K. Ramadan, G. L. Dianov
The paper identifies the NUCKS1-SKP2-p21/p27 axis as a checkpoint pathway regulating S phase entry by integrating mitogenic and DNA damage signals.
bioRxiv · Jun 29, 2021Cancer Biology