Unique Amphipathic α-helix Drives Membrane Insertion and Enzymatic Activity of ATG3
T. Nishimura, G. Lazzeri, N. Mizushima, R. Covino, S. Tooze
The paper identifies an amphipathic α-helix in ATG3 that facilitates membrane insertion and enzymatic activity essential for autophagosome formation.
bioRxiv · Feb 11, 2023 · PreprintCell Biology