mSWI/SNF interacts with the ribosome and its inhibition/mutations alter translation and sensitize to mTOR/PI3K inhibitors
L. Ulicna, S. C. Kimmey, C. M. Weber, G. M. Allard, S. C. Bendall, G. Crabtree, G. R. Bean, C. Van Rechem
This study shows mSWI/SNF complexes interact with the ribosome, alter translation, and increase sensitivity to mTOR/PI3K inhibitors in cancer cells with mutations.
bioRxiv · May 10, 2021 · PreprintCancer Biology