Systemic delivery of a CXCR4-CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy
M. S. Alghamri, K. Banerjee, A. A. Mujeeb, A. Taher, R. Thalla, B. L. McClellan, M. L. Varela, S. M. Stamatovic, G. Martinez-Revollar, A. Andjelkovic-Zochowska, J. V. Gregory, P. Kadiyala, A. Calinescu, J. A. Jimenez, A. A. Apfelbaum, , M. G. Castro
This paper develops synthetic protein nanoparticles delivering a CXCR4 inhibitor to treat glioma by enhancing immunotherapy and reducing tumor progression.
bioRxiv · Aug 27, 2021 · PreprintCell Biology