G. O. Akerele

Oral immunization of broilers with chitosan nano-encapsulated extracellular and cell wall proteins of necrotic enteritis-induced Clostridium perfringens

This study evaluates two chitosan-nanoparticle vaccines against Clostridium perfringens in broilers, showing increased antibody levels and reduced toxin levels but no significant impact on growth or mortality.

Chitosan nanoparticle vaccine loaded with crude extracellular proteins of C. perfringens and Salmonella flagella is partially protective against necrotic enteritis in broiler chickens.

A chitosan nanoparticle vaccine combining C. perfringens proteins and Salmonella flagella showed numerical but not statistically significant protection against necrotic enteritis in broiler chickens.