Author

G. P. Leary

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

B. R. Lyda· 1 shared B. Seaver· 1 shared C. S. Esslinger· 1 shared D. Silvius· 1 shared J. Farnsworth· 1 shared M. P. Kavanaugh· 1 shared N. R. Natale· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. R. Lyda

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivDec 14, 2021

Discovery and synthesis of hydroxy-L-proline based blockers of the neutral amino acid transporters SLC1A4 (ASCT1) and SLC1A5 (ASCT2).

M. P. Kavanaugh, B. R. Lyda, G. P. Leary…·J. Farnsworth

The paper identifies and synthesizes hydroxy-L-proline derivatives that selectively inhibit SLC1A4 and SLC1A5 amino acid transporters, with insights from computational docking and functional assays.

DOI 10.3390/molecules29102330

experimental assaystatistical model

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