Dysfunction of the Polycomb protein RYBP and of 5-methylcytosine oxidases leads to widespread CpG island hypermethylation and cell transformation
W. Cui, Z. Huang, S.-G. Jin, J. Johnson, G. Hostetter, G. P. Pfeifer
This study shows that dysfunction of RYBP and TET proteins causes CpG island hypermethylation and cell transformation in bronchial cells.
bioRxiv · Jul 26, 2022 · PreprintCancer Biology