Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration.
A.-L. Law, S. Jalal, T. Pallett, F. Mosis, A. Guni, S. Brayford, L. Yolland, S. Marcotti, J. Levitt, S. Poland, M. Rowe-Sampson, A. Jandke, R. Koechl, G. Pula, S. M. Ameer-Beg, , M. Krause
This study identifies NHSL1 as a negative regulator of Scar/WAVE-Arp2/3 activity, inhibiting lamellipodia stability and cell migration.
bioRxiv · May 11, 2020Cell Biology