Establishment of CD8+ T cell thymic central tolerance to tissue-restricted antigen requires PD-1
J. F. May, R. G. Kelly, A. Y. Suen, G. Rayat, C. C. Anderson, T. A. Baldwin
This study shows PD-1 is required for establishing central tolerance to tissue-restricted antigens in CD8+ T cells independent of clonal deletion.
bioRxiv · Aug 1, 2022Immunology