Author

T. A. Baldwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

C. C. Anderson· 2 shared C. W. Dessauer· 2 shared J. F. May· 2 shared K. Joannou· 2 shared R. G. Kelly· 2 shared A. B. Sundaram· 1 shared A. G. Carbajal· 1 shared A. Inoue· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

C. C. Anderson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Internal regulation between constitutively expressed T cell coinhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants

A. O. Adegoke, G. Thangavelu, T.-F. Chou, M. Petersen, K. Kakugawa, J. May, K. Joannou, Q. Wang, K. K. Ellestad, L. Boon, P. A. Bretscher, H. Cheroutre, M. Kronenberg, T. A. Baldwin, C. C. Anderson

This study identifies a regulatory pathway between BTLA and CD5 in T cells that calibrates their expression to establish self-tolerance in recent thymic emigrants.

Open Biology · Oct 30, 2024Peer-reviewedImmunology

Establishment of CD8+ T cell thymic central tolerance to tissue-restricted antigen requires PD-1

J. F. May, R. G. Kelly, A. Y. Suen, G. Rayat, C. C. Anderson, T. A. Baldwin

This study shows PD-1 is required for establishing central tolerance to tissue-restricted antigens in CD8+ T cells independent of clonal deletion.

bioRxiv · Aug 1, 2022Immunology

Popeye Domain-Containing Protein 1 Scaffolds a Complex of Adenylyl Cyclase 9 and the Two-Pore-Domain Potassium Channel TREK-1 in Heart

T. A. Baldwin, Y. Li, A. Marsden, R. F. R. Schindler, M. Zhang, A. G. Carbajal, M. A. Garcia, V. R. Venna, T. Brand, C. W. Dessauer

The paper identifies POPDC1 as a novel scaffold for AC9 that regulates heart rate by interacting with TREK-1 in an isoproterenol-dependent manner.

bioRxiv · Dec 21, 2021 · PreprintBiochemistry

γδ-Thymocyte Maturation and Emigration

K. Joannou, D. P. Golec, H. Wang, L. M. Henao-Caviedes, J. F. May, R. G. Kelly, R. Chan, S. C. Jameson, T. A. Baldwin

This study shows that adult mice have two distinct streams of γδ-T cells: one maturing in the periphery and another completing maturation in the thymus, with a fetal-derived resident population.

bioRxiv · Mar 19, 2021 · PreprintImmunology

G protein-regulated endocytic trafficking of adenylyl cyclase type 9

A. M. Lazar, R. Irannejad, T. A. Baldwin, A. B. Sundaram, J. S. Gutkind, A. Inoue, C. W. Dessauer, M. Von Zastrow

This study shows AC9 traffics from the plasma membrane to endosomes via Gs, unlike AC1, and contributes to cAMP production from endosomes.

bioRxiv · Apr 23, 2020Cell Biology