An altered metabolism could contribute to the low activation of neonatal CD8+T cells
J. A. Sanchez-Villanueva, O. Rodriguez-Jorge, O. Ramirez-Pliego, G. Rosas-Salgado, W. Abou-Jaoude, C. Hernandez, A. Naldi, D. Thieffry, M. A. Santana
The paper investigates how altered metabolism and ROS levels affect neonatal CD8+T cell activation, showing that lower ROS status explains reduced activation rates compared to adult cells.
bioRxiv · Aug 8, 2019 · PreprintImmunology