Author

D. Thieffry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Naldi· 2 shared M. A. Santana· 2 shared A. Akyol· 1 shared A. Isik· 1 shared A. Medina-Rivera· 1 shared A. Sanchez-Jimenez· 1 shared A. Uner· 1 shared A. V. Leon-Apodaca· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

A. Naldi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer

O. Saatci, R. Alam, K.-T. Huynh-Dam, A. Isik, M. Uner, N. Belder, P. G. Ersan, M. Cetin, U. M. Tokat, M. E. Gedik, H. Bal, O. S. Sahin, Y. Riazalhosseini, D. Thieffry, D. Gautheret, , O. Sahin

This study identifies LINC00152 as a driver of tamoxifen resistance in ER+ breast cancer by inhibiting ferroptosis, and shows that targeting LINC00152 restores sensitivity to tamoxifen.

bioRxiv · Nov 5, 2023Cancer Biology

Logical modeling of dendritic cells in vitro differentiation from human monocytes unravels novel transcriptional regulatory interactions

K. J. Nunez-Reza, A. Naldi, A. Sanchez-Jimenez, A. V. Leon-Apodaca, M. A. Santana, M. Thomas-Chollier, D. Thieffry, A. Medina-Rivera

The paper builds a logical model of human monocyte-to-dendritic cell differentiation using ChIP-seq and RNA-seq data to identify novel transcriptional regulatory interactions.

bioRxiv · Aug 14, 2020Immunology

An altered metabolism could contribute to the low activation of neonatal CD8+T cells

J. A. Sanchez-Villanueva, O. Rodriguez-Jorge, O. Ramirez-Pliego, G. Rosas-Salgado, W. Abou-Jaoude, C. Hernandez, A. Naldi, D. Thieffry, M. A. Santana

The paper investigates how altered metabolism and ROS levels affect neonatal CD8+T cell activation, showing that lower ROS status explains reduced activation rates compared to adult cells.

bioRxiv · Aug 8, 2019 · PreprintImmunology