Solvent Precipitation SP3 (SP4) enhances recovery for proteomics sample preparation without magnetic beads
H. E. Johnston, K. Yadav, J. M. Kirkpatrick, G. S. Biggs, D. Oxley, H. B. Kramer, R. S. Samant
This paper introduces SP4, a proteomics sample preparation method that replaces magnetic beads with solvent precipitation and centrifugation, improving protein recovery and reproducibility compared to SP3.
bioRxiv · Sep 24, 2021Biochemistry