Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation
Q. Ni, Z. Ge, Y. Li, G. Shatkin, J. Fu, K. Bera, Y. Yang, Y. Wang, A. Sen, Y. Wu, A. C. N. Vasconcelosi, A. P. Feinberg, K. Konstantopoulos, S. X. Sun
This study identifies a mechanism where cytoskeletal activation of NHE1 drives secondary volume increase and affects cell proliferation in response to hypotonic stress.
bioRxiv · Aug 31, 2023Biophysics