Argonaute-mediated system for supersensitive and multiplexed detection of rare mutations
Q. Liu, X. Guo, G. Xun, Z. Li, Y. Chong, L. Yang, H. Wang, F. Zhang, S. Luo, Z. Deng, K. Li, Y. Feng
This paper introduces A-Star, a method for detecting rare mutations with high sensitivity and multiplexing capability, achieving detection as low as 0.01% allele frequency.
bioRxiv · Feb 2, 2020 · PreprintBioengineering