Cell BiologybioRxiv
COP I and II dependent trafficking controls ER-associated degradation in mammalian cells
N. Ogen-Shtern, C. Chang, H. Saad…·G. Z. Lederkremer
The paper investigates COPI and COPII-dependent trafficking in ERAD by tracking proteins in the ERQC and shows differential effects of inhibiting these pathways on retrotranslocation and ERAD.
DOI 10.1016/j.isci.2023.106232