Zonal human hepatocytes are differentially permissive to Plasmodium falciparum malaria parasites
A. S.-P. Yang, Y. M. van Waardenburg, M. van de Vegte-Bolmer, G.-J. A. van Gemert, W. Graumans, H. H. W. de Wilt, R. W. Sauerwein
The paper shows that Plasmodium falciparum preferentially infects zone 3 hepatocytes expressing glutamine synthetase, highlighting metabolic differences in liver cell subtypes.
bioRxiv · Jun 29, 2020Microbiology