Fork Pausing Complex Engages Topoisomerases at the Replisome
Maksym Shyian, Benjamin Albert, Andreja Moset Zupan, Vitalii Ivanitsa, Gabriel Charbonnet, Daniel Dilg, David Shore
The paper shows that the Tof1-Csm3 complex recruits topoisomerase I to the replisome to promote fork pausing at replication fork barriers, independent of Rrm3 helicase.
bioRxiv · Aug 19, 2019Molecular Biology