Functional selection in a population of synthetic cells with a minimal metabolism
Thibault Di Méo, Louis Bunel, Gabriel Ragala, Mats van Tongeren, Rémi Sieskind, Christophe Danelon, Yannick Rondelez
The paper demonstrates that synthetic cells with minimal metabolism can undergo Darwinian evolution by filtering functional genotypes and mapping mutations in a key enzyme.
bioRxiv · Aug 25, 2025 · PreprintSynthetic Biology