Investigating Protein Degradability through Site-Specific Ubiquitin Ligase Recruitment
Olivia Shade, Amy Ryan, Gabriella Belsito, Alexander Deiters
This paper demonstrates a method to enhance protein degradation by recruiting E3 ligases to specific protein sites, showing improved degradation of target proteins and informing PROTAC development.
RSC Chemical Biology · Dec 13, 2024Peer-reviewedSynthetic Biology