Extended amygdala function is governed by threat probability, not uncertainty
Mesude Okhan, Kalina N. Kalinova, Kathryn A. DeYoung, Paige R. Didier, Zachary S. Scott, Dominique B. Ewing, Jordan Hassani, Jennifer V. Cunneen, Elisa Liu, Julia K. Earp, Gaby B. Castro, Jonathan A. Oler, Patrick H. Roseboom, Connor W. Christensen, Carly M. Drzewiecki, , Andrew S. Fox
The paper challenges the canonical model of anxiety by showing that threat probability, not uncertainty, is more strongly associated with threat anticipation and EA regions.
bioRxiv · Oct 5, 2026 · PreprintNeuroscience