Andrew S. Fox

The paper challenges the canonical model of anxiety by showing that threat probability, not uncertainty, is more strongly associated with threat anticipation and EA regions.

The paper analyzes fMRI data to investigate the role of the extended amygdala in threat processing, finding no strict functional segregation between the central nucleus and bed nucleus of the stria terminalis.

The paper identifies heightened subcortical reactivity to uncertain-threat as a predictor of future internalizing symptoms in individuals with low stress exposure.

This paper demonstrates that certain and uncertain threat anticipation recruit a shared neural circuit with distinct activation dynamics in humans.

This study creates normative brain growth charts for rhesus macaques across their lifespan using MRI data, revealing developmental milestones and cross-species comparisons with humans.

The paper investigates the neural basis of neuroticism/negative emotionality by showing its association with heightened BST activation during uncertain threat anticipation, not the amygdala.

The paper uses machine learning to link infant rhesus monkey temperament with peri-adolescent brain metabolism and defensive behavior.

The paper shows that pubertal androgen exposure programs adult behavioral responses to social defeat stress, with effects mediated by the bed nucleus of the stria terminalis.

The paper links greater activation in a cingulo-opercular circuit during an anxiety-eliciting task with reduced daily stressor-related distress in individuals.

The paper shows infant inhibited temperament in monkeys predicts adult behavior, is heritable, and links to anxiety-related genetic variants.

The paper develops a transfer-learning U-Net model for brain extraction in non-human primates using human data, achieving better performance than traditional methods and popular MRI packages.

This study investigates the neural circuits involved in anticipating temporally uncertain and certain threat, revealing co-localized but functionally distinct brain regions associated with anxiety.

The paper identifies 528 AT-related transcripts in rhesus monkey CeL neurons, including PKCδ, and shows their projection to BSTLd, suggesting a primate circuit relevant to anxiety.

This study shows that acute alcohol reduces threat-related brain activity in the central extended amygdala in humans, specifically in the BST and Ce regions.

The paper maps the intrinsic functional connectivity of the central extended amygdala in healthy adults, revealing distinct patterns between the BST and Ce and their connections to prefrontal and subcortical regions.