Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network
Miriam Pagin, Mattias Pernebrink, Simone Giubbolini, Cristiana Barone, Gaia Sambruni, Yanfen Zhu, Matteo Chiara, Sergio Ottolenghi, Giulio Pavesi, Chia‐Lin Wei, Claudio Cantù, Silvia K. Nicolis
This study identifies Fos as a key regulator of neural stem cell self-renewal, showing it rescues proliferation and interacts with Sox2 through a gene regulatory network involving Socs3.
Stem Cells · Mar 29, 2021Peer-reviewedGenetics