PET by MRI: Glucose Imaging by 13C-MRS without Dynamic Nuclear Polarization by Noise Suppression through Tensor Decomposition Rank Reduction
Jeffrey R. Brender, Shun Kishimoto, Hellmut Merkle, Galen Reed, Ralph E. Hurd, Albert P. Chen, Jan Henrik Ardenkjaer-Larsen, Jeeva Munasinghe, Keita Saito, Tomohiro Seki, Nobu Oshima, Kazu Yamamoto, Peter L. Choyke, James Mitchell, Murali C. Krishna
This paper introduces a method to image glucose metabolism using 13C-MRS with tensor decomposition to enhance signal-to-noise ratio, enabling non-hyperpolarized imaging of the Warburg effect with high temporal and spatial resolution.
bioRxiv · Feb 15, 2018 · PreprintCancer Biology