Early neuronal reprogramming and cell cycle reentry shape Alzheimer's disease progression
Roi Meir, Gali Schwartz, Miriam Adam, Adi Avni Lapidot, Anael Cain, Gilad Sahar Green, Vilas Menon, David A. Bennett, Philip L. De Jager, Naomi Habib
The paper identifies early transcriptional changes in neuronal subtypes in Alzheimer's disease using single-nucleus RNA data, revealing distinct programs linked to vulnerability and resilience.
bioRxiv · Jun 4, 2025 · PreprintNeuroscience