Author

Anael Cain

Hebrew University of JerusalemORCID 0000-0003-1927-4370Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:clustering· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:trajectory inference· 2

Frequent Co-Authors

Naomi HabibiD· 4 shared Gilad Sahar GreeniD· 3 shared Philip L. De JageriD· 3 shared Vilas MenoniD· 3 shared Aviv RegeviD· 2 shared Charles C. WhiteiD· 2 shared Cristin AubiniD· 2 shared David Alan BennettiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersNeuroscience

Naomi HabibORCID

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4 papers

Recent·Most cited

BioinformaticsbioRxivPreprintDec 17, 2025

DeepDynamics resolves cell-subtype and clinicopathological dynamics from bulk RNA-seq to identify mediators of Alzheimer's disease risk

Yifat Hodaya Haddad, Yuval Asher Rom, Gilad Sahar Green…·Naomi Habib

DeepDynamics uses bulk RNA-seq and sc/snRNA-seq to infer cell-subtype and clinicopathological dynamics in Alzheimer's disease, identifying risk mediators in APOE4 carriers.

DOI 10.64898/2025.12.15.694345

humanbulk RNA-seq

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NeurosciencebioRxivPreprintJun 4, 2025

Early neuronal reprogramming and cell cycle reentry shape Alzheimer's disease progression

Roi Meir, Gali Schwartz, Miriam Adam…·Naomi Habib

The paper identifies early transcriptional changes in neuronal subtypes in Alzheimer's disease using single-nucleus RNA data, revealing distinct programs linked to vulnerability and resilience.

3 citations

humansnRNA-seq

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NeuroscienceAlzheimer s & DementiaPeer-reviewedDec 1, 2023

Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer's disease

Gilad Sahar Green, Masashi Fujita, Hyun-Sik Yang…·Philip L. De Jager

The paper identifies two distinct aging trajectories in the human brain linked to Alzheimer's disease or alternative aging, using single-nucleus RNA-seq data and causal modeling.

51 citationstop 3%

humanscRNA-seq

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NeuroscienceNature NeurosciencePeer-reviewedJun 19, 2023

Multi-cellular communities are perturbed in the aging human brain and with Alzheimer's disease

Anael Cain, Mariko F. Taga, Cristin Aubin…·Philip L. De Jager

The paper maps cellular changes in the aging human brain and identifies altered multicellular communities in Alzheimer's disease using single nucleus RNA-seq and bulk RNA-seq data.

143 citationstop 1%

humanscRNA-seq

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