snpXplorer: haplotype-block representation of GWAS signals for integrated variant and cross-trait interpretation
Niccoló Tesi, Gilad Sahar Green, Alex Salazar…·Marcel J. T. Reinders
Author
Hebrew University of JerusalemORCID 0009-0002-3507-7684Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Niccoló Tesi, Gilad Sahar Green, Alex Salazar…·Marcel J. T. Reinders
Loren Dos Santos, Ricardo A. Vialle, Natacha Comandante-Lou…·Kátia de Paiva Lopes
The paper analyzes microglial communication in Alzheimer's disease using single-nucleus RNA sequencing to identify altered signaling pathways and cell interactions associated with disease pathology.
Yifat Hodaya Haddad, Yuval Asher Rom, Gilad Sahar Green…·Naomi Habib
DeepDynamics uses bulk RNA-seq and sc/snRNA-seq to infer cell-subtype and clinicopathological dynamics in Alzheimer's disease, identifying risk mediators in APOE4 carriers.
Roi Meir, Gali Schwartz, Miriam Adam…·Naomi Habib
The paper identifies early transcriptional changes in neuronal subtypes in Alzheimer's disease using single-nucleus RNA data, revealing distinct programs linked to vulnerability and resilience.
Gilad Sahar Green, Masashi Fujita, Hyun-Sik Yang…·Philip L. De Jager
The paper identifies two distinct aging trajectories in the human brain linked to Alzheimer's disease or alternative aging, using single-nucleus RNA-seq data and causal modeling.
Masashi Fujita, Zongmei Gao, Lu Zeng…·Philip L. De Jager
The paper identifies cell-type and cell-subtype specific eQTLs in aging human cortex, revealing variant effects on gene expression and disease associations.