The major role of the REL2/NF-κB pathway in the regulation of midgut bacterial homeostasis in the malaria vector Anopheles gambiae
Suzana Zaković, Galo E. Rivera, Remmora Gomaid, Cristina Graham Martínez, Christine Kappler, Éric Marois, Elena A. Levashina
This study shows that REL2/NF-κB signaling regulates midgut bacterial homeostasis in Anopheles gambiae, with loss of REL2 causing dysbiosis and reduced Plasmodium falciparum prevalence.
Cell Reports · Sep 1, 2025Peer-reviewedImmunology